abstract：:The burrowing sponges Anthosigmella varians and Spheciospongia vesparium were found to be rich in the isoprenoid phospholipid fatty acid 4,8,12-trimethyltridecanoic (5.2% and 23%, respectively, of the total fatty acid composition), while the burrowing sponge Chondrilla nucula and the demosponge Agelas dispar contained...

journal_title：Lipids

authors： Carballeira NM,Maldonado L,Porras B

更新日期：1987-10-01 00:00:00

abstract：:After administering the equivalent of 1 g of eicosapentaenoic acid (EPA) in four different chemical forms, the kinetics of EPA incorporation into plasma triglycerides (TG) were compared by gas liquid chromatography on a capillary column following separation of the lipid fraction by thin layer chromatography. EPA incor...

journal_title：Lipids

authors： el Boustani S,Colette C,Monnier L,Descomps B,Crastes de Paulet A,Mendy F

更新日期：1987-10-01 00:00:00

abstract：:The activity of lysosomal acid cholesteryl ester hydrolase (acid CEH, EC 3.1.1.13) in rat liver was determined at 3, 5, 7, 10 and 20 wk following birth. The levels of acid CEH activity showed a marked decrease as rats grew older, whereas those of other lysosomal marker enzymes, such as acid phosphatase, beta-glucuroni...

journal_title：Lipids

authors： Tanaka M,Iio T,Tabata T

更新日期：1987-09-01 00:00:00

abstract：:The synthesis of alkyl chain-substituted thiazanones from oxo fatty esters and a long chain aldehyde is reported. Four oxo compounds-methyl 10-oxoundecanoate, methyl 9-oxooctadecanoate, methyl 9,10-dioxooctadecanoate and octadecanal-were allowed to react with β-mercaptopropionic acid in the presence of ammonium carbon...

journal_title：Lipids

authors： Khan A,Husain SR,Ahmad F,Siddiqui MS,Pimlott W

更新日期：1987-08-01 00:00:00

abstract：:The sciatic nerve of rats fed sunflower oil (6 mg 18:3-n-3/100 g of diet) presented dramatic alterations in the long chain polyunsaturated fatty acids in comparison with those fed soy oil (130 mg 18:3n-3/100 g of diet). In both 15-day-old and 60-day-old animals fed sunflower oil, 22:6n-3 (cervonic acid) was four-fold ...

journal_title：Lipids

authors： Bourre JM,Youyou A,Durand G,Pascal G

更新日期：1987-07-01 00:00:00

abstract：:Dietary lipids, in particular unsaturated fat, promote the development of many experimental tumors. However, no mechanisms to fully explain these effects have been elucidated. Recent reports, which we summarize here, suggest a role for gap junction-mediated intercellular communication in the process of tumor promotion...

journal_title：Lipids

authors： Aylsworth CF,Welsch CW,Kabara JJ,Trosko JE

更新日期：1987-06-01 00:00:00

abstract：:The effect of age and dietary fat type on tocopherol status was investigated using young and old C57BL/6Nia mice fed semipurified diets containing 5% (by weight) fish, corn or coconut oils and supplemented with 30, 100 or 500 ppm dl-alpha-tocopheryl acetate for 6 wk. Tocopherol levels in the diets, plasma, liver, kidn...

journal_title：Lipids

authors： Meydani SN,Shapiro AC,Meydani M,Macauley JB,Blumberg JB

更新日期：1987-05-01 00:00:00

abstract：:The amount of docosahexaenoate (22:6n-3)-containing phospholipid species decreases with aging in the rat retina. Most lipids, but especially choline and serine glycerophospholipids, show a significant fall in 22:6n-3, which is not compensated by increases in other polyenoic fatty acids. The decrease not only affects 2...

journal_title：Lipids

authors： Rotstein NP,Ilincheta de Boschero MG,Giusto NM,Aveldaño MI

更新日期：1987-04-01 00:00:00

abstract：:Feline omental lipid extracts, previously reported to be angiogenic in the cornea of rabbits, were fractionated and the major lipid components characterized. Approximately 97% of the chloroform/methanol extract consisted of triglycerides containing primarily 16:0, 18:0, 18:1 and 18:2 fatty acids. Trace quantities of f...

journal_title：Lipids

authors： McCluer RH,Evans JE,Williams M,Griffith AL,Catsimpoolas N

更新日期：1987-04-01 00:00:00

abstract：:A method was developed to analyze and quantify volatile fatty acids (VFA) such as acetic, propionic, butyric, isobutyric, valeric and isovaleric acids in biological specimens. To obtain good sample transfer into the chromatographic system an organic solvent had to be used together with an aqueous milieu, thus improvin...

journal_title：Lipids

authors： Fleming SE,Traitler H,Koellreuter B

更新日期：1987-03-01 00:00:00

abstract：:The developmental changes in the fatty acid composition of ethanolamine phosphoglycerides (EPG) and choline phosphoglycerides (CPG) were studied in the liver and brain of 18 newborn infants with gestational ages ranging from 20 to 44 wk. A small group of five newborns receiving total parenteral nutrition (TPN) with hi...

journal_title：Lipids

authors： Martínez M,Ballabriga A

更新日期：1987-03-01 00:00:00

abstract：:Two new fatty acid metabolites, 5(Z),7(E),9(E),14(Z),17(Z)-icosapentaenoic acid and 5(E),7(E),9(E),14(Z),17(Z)-icosapentaenoic acid, have been isolated from the temperate red marine alga, Ptilota filicina (Ceramiales, Rhodophyta). The structures of these new compounds, isolated as their methyl ester derivatives, have ...

journal_title：Lipids

authors： Lopez A,Gerwick WH

更新日期：1987-03-01 00:00:00

abstract：:Cholesteryl esterase activities were determined in homogenates of rat heart (ventricles), isolated, calcium-tolerant, cardiac myocytes and aortic tissue and were compared with acid and neutral triglyceride lipase activities in these fractions. Using cholesteryl oleate/phosphatidylcholine/taurocholate emulsions and dig...

journal_title：Lipids

authors： Stam H,Broekhoven-Schokker S,Schoonderwoerd K,Hülsmann WC

更新日期：1987-02-01 00:00:00

abstract：:In vivo intestinal perfusion was used to follow the absorption of three different choline glycerophospholipids (CGP) in guinea pig. These included 1-[3H]palmitoyl-2-acyl-sn-glycero-3-phosphocholine (diacyl-GPC), 1-[3H]-O-hexadecyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) and 1,2-di-O-hexadecyl-sn-glycero-3-p...

journal_title：Lipids

authors： Diagne A,Mitjavila S,Fauvel J,Chap H,Douste-Blazy L

更新日期：1987-01-01 00:00:00

abstract：:Bile acids solubilize proteins from liver plasma membrane both in vivo and in vitro. The ability to solubilize the proteins is dependent on the species of bile acid. In this paper, the effect of phospholipid on the solubilization of a membrane-bound enzyme by bile acids was investigated in vitro. Taurocholate (TC) and...

journal_title：Lipids

authors： Nokubo M

更新日期：1987-01-01 00:00:00

abstract：:We have investigated the regulation of cholesterol synthesis in isolated human small intestine epithelial cells (enterocytes). It was established that the amount of cholesterol synthesized increased linearly with the incubation time and the number of cells in the incubation mixture; the synthesis was suppressed by 7-k...

journal_title：Lipids

authors： Sviridov DD,Safonova IG,Talalaev AG,Repin VS,Smirnov VN

更新日期：1986-12-01 00:00:00

abstract：:The pyrrolidide and picolinyl ester derivatives of the fatty acids in two natural lipid samples rich in unsaturated fatty acids, pig testis lipids and cod liver oil were satisfactorily resolved on capillary columns of fused silica coated with stationary phases of varying polarity. The picolinyl esters, in particular, ...

journal_title：Lipids

authors： Christie WW,Brechany EY,Johnson SB,Holman RT

更新日期：1986-10-01 00:00:00

abstract：:Gallstone formation and dissolution were studied in a prairie dog model of cholesterol (CH) cholelithiasis. Gallstones were induced in 49 prairie dogs by feeding 1.2% CH in a nutritionally adequate semisynthetic diet for 6 wk (period 1). At 6 wk, gallstones had developed in all animals examined. The diets were modifie...

journal_title：Lipids

authors： Cohen BI,Mosbach EH,McSherry CK,Rzigalinski B,Kuroki S

更新日期：1986-09-01 00:00:00

abstract：:The effect of various physicochemical forms of substrate on the activity of acid cholesteryl ester hydrolase isolated from rat liver lysosomes was studied. The amount of sodium taurocholate was varied in the substrate mixture which contained constant amounts of egg phosphatidylcholine (PC) and cholesteryl oleate. The ...

journal_title：Lipids

authors： Klemets R,Lundberg B

更新日期：1986-08-01 00:00:00

abstract：:The conversion of [14C]-labeled compounds such as acetate, glucose, pyruvate and palmitate into CO2, glyceride-glycerol, glyceride fatty acids and total lipids was monitored in the average and matching adipocyte (with respect to size) preparations from young (6-9 wk) and old (age 56-60 wk) male Sprague-Dawley rats. Th...

journal_title：Lipids

authors： Jamdar SC,Osborne LJ,Wells GN

更新日期：1986-07-01 00:00:00

abstract：:The anesthetic potency of four derivatives of n-octane was measured by tadpole righting reflex and expressed as effective millimolar concentration of drug in membrane, EDM50. Potency diminished (ED50 increased) in this order: 1-octanol, EDM50 = 5.5; 1-(2-methoxyethoxy)octane, EDM50 = 28; 1-methoxyoctane, EDM50 = 61; a...

journal_title：Lipids

authors： Brockerhoff H,Brockerhoff S,Box LL

更新日期：1986-06-01 00:00:00

abstract：:An analysis of the lipids in swine influenza vaccines was performed, comparing six different lots of swine influenza, other influenza and noninfluenza vaccines. Cholesterol content and phospholipid content varied greatly, but there were no major differences between the types of vaccines. Appreciable amounts of phospha...

journal_title：Lipids

authors： Leskawa KC,Hogan EL,Dasgupta S,Chien JL,Erwin RE,Brostoff SW

更新日期：1986-05-01 00:00:00

abstract：:Azaserine induced two phenotypically different populations of foci, namely, acidophilic and basophilic foci. The effects of dietary modification during the post-initiation phase of carcinogenesis were examined. A diet of 20% (w/w) unsaturated fat (unsat) compared to a 20% saturated fat (sat) diet or a control diet (5%...

journal_title：Lipids

authors： Roebuck BD

更新日期：1986-04-01 00:00:00

abstract：:Interest in malondialdehyde (MDA) metabolism stems from its formation as a product of lipid peroxidation in the diet and in the tissues; its reactivity with functional groups of nucleic acid bases, proteins and phospholipids; its mutagenicity in bacteria, and its reported skin and liver carcinogenicity in animals. Adm...

journal_title：Lipids

authors： Draper HH,McGirr LG,Hadley M

更新日期：1986-04-01 00:00:00

abstract：:The effect of dexamethasone on the incorporation and conversion of [1-14C]eicosa-8,11,14-trienoic acid to arachidonic acid in isolated hepatocytes and in hepatoma tissue culture (HTC) cells was studied. In both kinds of cells, no changes in the exogenous acid incorporation were found when the hormone was added to the ...

journal_title：Lipids

authors： Marra CA,de Alaniz MJ,Brenner RR

更新日期：1986-03-01 00:00:00

abstract：:The ganglioside and neutral glycosphingolipid composition of adult monkey small and large intestinal mucosa were characterized and compared. GM3, GM2 and GD1A were found to be the principal gangliosides in each of these tissues. Dihexosylceramide was the major neutral glycosphingolipid of both organs. The total conten...

journal_title：Lipids

authors： Dahiya R,Brown MD,Brasitus TA

更新日期：1986-02-01 00:00:00

abstract：:The major sterols of the seeds ofBenincasa cerifera, Cucumis sativus, Cucurbita maxima, C. pepo andTrichosanthes japonica and of the mature plant tissues (leaves and stems) ofCitrullus battich, Cucumis sativus andGynostemma pentaphyllum of the family Cucurbitaceae were 24-ethyl-Δ(7)-sterols which were accompanied by s...

journal_title：Lipids

authors： Akihisa T,Thakur S,Rosenstein FU,Matsumoto T

更新日期：1986-01-01 00:00:00

abstract：:The effects of hyper- and hypothyroidism on enzyme activities involved in phospholipid metabolism in the rat liver were studied. Hyperthyroidism significantly decreases activities of both microsomal acyl-CoA:glycero-3-phosphate acyltransferase (GPAT) (34%, p less than 0.01) and microsomal acyl-CoA:1-acylglycero-3-phos...

journal_title：Lipids

authors： Dang AQ,Faas FH,Carter WJ

更新日期：1985-12-01 00:00:00

abstract：:The incorporation of arachidonic acid (AA) as compared to eicosapentaenoic acid (EPA) into human platelet phospholipids was tested by incubating washed platelets with a known mixture of [3H]AA and [14C]EPA. Following incubation, the platelet lipids were extracted, the individual phospholipids--phosphatidylcholine (PC)...

journal_title：Lipids

authors： Weaver BJ,Holub BJ

更新日期：1985-11-01 00:00:00

abstract：:In animals, non-sterol metabolites of the mevalonate pathway act independently from receptor-mediated cholesterol uptake in the multivalent feedback regulation of mevalonate biosynthesis. Studies leading to the isolation and characterization of plant-borne suppressors of mevalonate biosynthesis are reviewed. We propos...

journal_title：Lipids

authors： Qureshi AA,Burger WC,Peterson DM,Elson C

更新日期：1985-11-01 00:00:00

abstract：:The purpose of the present study was to investigate the effects of gamma linolenic acid (GLA) on cardiovascular responses to psychosocial stress (isolation) and to pressor hormones in the genetically borderline hypertensive rat (SHR X WKY). Adult male SHR X WKY were divided into two groups following five weeks of grou...

journal_title：Lipids

authors： Mills DE,Summers MR,Ward RP

更新日期：1985-09-01 00:00:00

abstract：:The phospholipid composition of gill tissue from thermally acclimated rainbow trout, Salmo gairdneri, was determined by Iatroscan analysis following an initial development of the chromarods in a non-polar solvent to remove neutral lipids. Standard curves for all phospholipids, although linear through most of the conce...

journal_title：Lipids

authors： Hazel JR

更新日期：1985-08-01 00:00:00

abstract：:Primary cultured hepatocytes from normal mice and mice with Sarcoma 180 were characterized. The viability of freshly isolated hepatocytes from both sources was over 90% and the cells had a relatively stable population of DNA for a minimum of three days. After incubation with (3H)leucine, the syntheses and secretions o...

journal_title：Lipids

authors： Masuno H,Okuda H

更新日期：1985-07-01 00:00:00

abstract：:This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. We found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate fro...

journal_title：Lipids

authors： Brautigan DL,Randazzo P,Shriner C,Fain JN

更新日期：1985-07-01 00:00:00

abstract：:A pilot study was undertaken to determine if moderate changes in linoleate (18:2 omega 6) intake would modulate the prostaglandin E turnover concurrently with, or independently of, changes in the plasma prostaglandin (PG) precursor levels. Four adult male volunteers in good health were fed two controlled diets contain...

journal_title：Lipids

authors： Ferretti A,Judd JT,Marshall MW,Flanagan VP,Roman JM,Matusik EJ Jr

更新日期：1985-05-01 00:00:00

abstract：:Geometric and positional isomers of [1-14C] octadecenoic acids have been synthesized by modifications of published procedures. Positional isomers of octadecynoic acids also have been synthesized to obtain the geometric and positional isomers of the unlabeled octadecenoic acid analogs. The syntheses were accomplished b...

journal_title：Lipids

authors： Valicenti AJ,Pusch FJ,Holman RT

更新日期：1985-04-01 00:00:00

abstract：:This study addresses two questions: 1) what is the maximum amount of tocopherol that can be contained in egg phosphatidylcholine liposomes, and 2) what is the stability of these vesicles in the presence of serum proteins? These liposomes, made with a French pressure cell, can contain no more than 33 mol% of tocopherol...

journal_title：Lipids

authors： Halks-Miller M,Guo LS,Hamilton RL Jr

更新日期：1985-03-01 00:00:00

abstract：:The diurnal variation in lysosomal acid cholesteryl ester hydrolase (Acid CEH), (EC 3.1.1.13) has been examined in fed, fasted and adrenalectomized rats. The Acid CEH activity of normal rat liver exhibits a diurnal rhythm with maxima at 06.00 hours and minima at 18.00 hours, but such a rhythm was not observed in splee...

journal_title：Lipids

authors： Tanaka M,Yonekura R,Iio T,Tabata T

更新日期：1985-01-01 00:00:00

abstract：:Several water soluble and organic solvent soluble fluorescent peaks were observed in extracts of uteri from vitamin E deficient or supplemented rats following Sephadex column chromatography and spectrophotofluorometric analysis. Levels of one of the organic and two of the water soluble fluorescent peaks were found to ...

journal_title：Lipids

authors： Csallany AS,Ayaz KL,Menken BZ

更新日期：1984-12-01 00:00:00

abstract：:The conversion of labeled palmitic, linoleic, arachidonic and docosahexaenoic acids to their respective acyl CoA's was studied in homogenates and microsomes of rat tissues. The highest activity, both in homogenates and microsomes, was seen in liver and heart. There was moderate activity in retina, brain, lung, kidney ...

journal_title：Lipids

authors： Reddy TS,Bazan NG

更新日期：1984-12-01 00:00:00